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Stem Cells for Knee Arthritis Fracture
Stem Cell case of a 71 year old with knee arthritis, pain, and a fracture
on MRI with before and after stem cell injection MRI imaging showing
resolution of bone marrow edema and fracture.

71 year old active male presented to New Jersey Sports Medicine with
complaint of pain in his left knee for 2 years.  He had an MRI from
another physician performed earlier that month.

MRI LEFT KNEE report by board certified radiologist from January
2019: “There is diffuse chondral thinning compatible with moderate
arthrosis.  There is a focus of subchondral linear low signal along the far
medial weight-bearing femoral condyle with extensive surrounding
osseous edema. This may reflect focal degenerative change versus early
subchondral insufficiency fracture”. See images below.

BMA Stem Cell procedure on the arthritis knee was performed by Dr.
Marc Silberman at New Jersey Sports Medicine in  February 2019.

One month post procedure with injection of stem cells from bone
marrow aspirate the athlete reported that he no longer had any pain with
stairs and reported stiffness was only temporary after prolong sitting,
pain was no longer constant, there was no more night pain, and walking
was better.

MRI LEFT knee 8/2019 reported by radiologist compared to prior
imaging: “There is interval healing of the previously described
subchondral insufficiency fracture with  near complete resolution of
osseous stress edema”.  See images below.


























































While case reports of stem cells for knee arthritis are encouraging, more
scientific randomized clinical controlled studies are needed.
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Extensive bone marrow edema (large white
area seen anterior) in arthritic  knee in
femoral condyle with fracture line, linear
low signal dark fracture seen prior to bone
marrow stem cell injection.
Post stem cell injection into arthritis knee
the bone marrow edema (white area in
femoral condyle) is no longer seen, bone is
all dark normal signal.
Extensive bone marrow edema (large white
area seen anterior) in arthritis knee in
femoral condyle with fracture line, linear
low signal dark fracture seen prior to bone
marrow stem cell injection.
Post stem cell injection into arthritis knee
the bone marrow edema (white area in
femoral condyle) is no longer seen, bone is
all dark normal signal.
Abnormal signal in same arthritis knee in
femoral condyle on T1 imaging, where
bone should be white you see a large focal
abnormal low signal dark black abnormality
(arrow) seen in knee prior to bone marrow
stem cell injection.
Post bone marrow stem cell injection the
abnormal signal in same arthritis knee in
femoral condyle on T1 imaging is no
longer seen, bone is all white again in knee
treated with bone marrow stem cell
injection.